How to fix "Cannot start Microsoft Outlook. Unable to open Outlook window" error

Recover the Navigation Pane configuration file

In most cases it is the corrupted Navigation Pane settings file that prevents Outlook from starting successfully, so the first thing you need to do is to mend it. Here's how you can do this on different operating systems:

1. If you use Vista, Windows 7 or Windows 8, click the Start button. On Windows XP, click Start > Run.
2. Type the following command in the search field:

   outlook.exe /resetnavpane

   Note: Be sure to enter a space between outlook.exe and /resetnavpane.

3. Press Enter or click on the file in order to reset the Navigation Pane settings and then open Outlook.

If you prefer to work with the Run dialog on Windows 7 or Windows 8, then follow this way.

1. On the Start menu, click All Programs > Accessories > Run.
2. Type the outlook.exe /resetnavpane command and click OK.

   Note: An automatic fix for "Outlook unable to start" problem is available of Microsoft's site for Windows 8, Windows 7, Windows Vista and Windows XP. Simply click "Fix this problem" link on this page.

Delete the Navigation pane settings file
If for some reason you were not able to recover the Navigation pane configuration file, nor did the automatic fix provided by Microsoft work, try to delete the XML file that stores the navigation pane settings. To do this, proceed with the following steps:

1. Enter the below command in the Start > Search field on Windows 7 and Windows 8 (or Start > Run on Windows XP) and press Enter:

   %appdata%\Microsoft\Outlook

2. This will open the folder where Microsoft Outlook configuration files are stored. Find and delete the Outlook.xml file.

   Warning! Do try to recover the Navigation pane settings file first. Consider deleting as the last resort, if nothing else works.

Repair your Outlook data files (.pst and .ost) using the Inbox Repair tool

If you have reinstalled Outlook recently and something went wrong during uninstallation of the previous version, the default Outlook data file (.pst / .ost) might have been deleted or damaged, which is why Outlook won't open. In this case you are likely to get this error: "Cannot start Microsoft Office Outlook. The file Outlook.pst is not a personal folders file."

Let's try to repair your outlook.pst file using Scanpst.exe, aka Inbox Repair tool.

1. Open Windows Explorer and navigate to C:\Program Files\Microsoft Office\{Office version}. If you have 64-bit Windows with 32-bit Office installed, go to C:\Program Files x86\Microsoft Office\{Office version}.
2. Find Scanpst.exe in the list and double click on it.

   Alternatively, you can click Start and type scanpst.exe in the Search box.

3. Click the Browse button to select your default Outlook.pst file.

   In Outlook 2010 - 2019, the PST file resides in the Documents\Outlook Files folder. If you upgraded to Outlook 2010 on a computer that already had data files created in previous versions, you will find the outlook.pst file in a hidden folder in these locations:

   • On Windows Vista, Windows 7 and Windows 8" - C:\Users\user\AppData\Local\Microsoft\Outlook
   • On Windows XP, you will find it here C:\ Documents and Settings\user\Local Settings\Application Data\Microsoft\Outlook
   

You can find more details about repairing the Outlook PST file on Microsoft's web-site: Repair Outlook Data Files (.pst and .ost).

Try to open Outlook and if it starts without errors, congratulations! You do not need the remainder of this article : ) Or maybe, it's worth to bookmark it for the future.

Turn off Compatibility mode in Outlook

When it comes to using compatibility mode in Outlook, let me quote a wisdom that Outlook's guru Diane Poremsky shared on her blog: "If you enabled compatibility mode, disable it. If you haven't, don't even consider it."

You can turn off compatibility mode in the following way:

1. Click the Start button (or Start > Run on Windows XP) and type outlook.exe in the search field.

   Alternatively, you can find outlook.exe in the default installation folder: C:\Program Files\Microsoft Office\{Office version}. Where {Office version} is Office15 if you are using Office 2013, Office14 for Office 2010 and so on.

2. Right-click on OUTLOOK.EXE, and then click Properties.
3. Switch to the Compatibility tab and be sure to clear the "Run this program in compatibility mode for" check box.
4. Click OK and try to start Outlook.

If you still cannot open the Outlook window and the same "Cannot start Microsoft Office Outlook" error persists, try to restore the previous version of the PST file. Of course, in this case some of your recent emails and appointments will be lost, but it seems to be a better alternative than no Outlook at all. So, right click on the Outlook.pst file and select Restore Previous Versions.

Create a new Outlook profile

If neither repairing nor restoring the Outlook.pst file worked, you can create a new mail profile in order to see if it solves the problem. If it does, then you can copy your current Outlook data file (.pst or .ost) from the broken mail profile to the newly created one.

1. Create a new profile by going to Control Panel > Mail > Data Files > Add...

   For full details, see Microsoft's step-by-step guidance on creating a new Outlook profile.

2. Set the new profile as the default one. On the "Account Setting" dialog > Data files tab, select the new profile and click the Set as Default button on the toolbar.

   After you do this, a tick will appear to the left of the newly created profile, as you see in the screenshot below.

3. Try to open Outlook and if it starts normally with the newly created profile, copy the data from your old .pst file as explained in the next step, and continue working with it.
4. Import data from the old Outlook PST file. Hopefully, now you can finally open Outlook but your PST file is new and therefore empty. Don't panic, this is not a problem at all compared to the one you've just solved : ) Perform the following steps to copy emails, calendar appointments and other items from your old .pst file.
   • Go to File > Open > Import.
   • Select "Import from another program of file" and click Next.
   • Choose "Outlook DataFile (.pst)" and click Next.
   • Click the Browse button and select your old .pst file. If you've had just one Outlook profile and never renamed the PST file, then most likely it will be Outlook.pst.
5. Click Next and then Finish to complete the migration process.

   Warning! If your old Outlook PST file was severely damaged and the repair procedure was not successful, you may get "Cannot start Microsoft Outlook. The set of folders cannot be opened" error again. If this case, the only way is to create a new profile and use it without importing data from the old .pst file.

If your old .pst file contains very important data that you absolutely cannot live without, you can try some third-part tools to repair your PST file, e.g. described in this article: Five reliable Outlook PST file repair tools. I cannot recommend any particular tool because luckily have never had to use any on my own machine.

Start Outlook in Safe Mode without any extensions

Starting Outlook in Safe Mode actually means that it will be run without any add-ins that are currently installed on your machine. It is the fastest way to determine if the problem on Outlook start up is caused by some of the add-ins.

To open Outlook in safe mode, click on its icon holding the Ctrl key, or click paste outlook /safe in the search box and press Enter. Outlook will display a message asking you to confirm that you really want to start it in safe mode, click Yes.

An alternative way is to use the outlook.exe /noextensions command, which basically means the same - start Outlook without any extensions.

If Outlook starts fine in safe mode, the problem is definitely with one of your add-ins. Try to disable the add-ins one at a time to detect which one is causing the problem. You can find the detailed information in : How to disable Outlook add-ins.

A fix for "Cannot start Outlook. MAPI32.DLL is corrupt" error

As the error description explains, this error happens if you have a corrupted or outdated MAPI32.DLL installed on your machine. Usually this happens when you'd installed a newer version of Microsoft Office and then installed an older one.

The entire text of the error message is this: "Cannot start Microsoft Office Outlook. MAPI32.DLL is corrupt or the wrong version. This could have been caused by installing other messaging software. Please reinstall Outlook."

To fix the MAPI32.DLL error, perform the following steps:

• Open C:\Program Files\Common Files\System\Msmapi\1033
• Delete MAPI32.DLL
• Rename MSMAPI32.DLL to MAPI32.DLL

Start Outlook and the error should be gone.

A fix for Exchange Server errors

If you work in a corporate environment and your company uses an Outlook Exchange server, then the "unable to open Outlook" problem may be caused by something known as Cached Exchange Mode. When the Cached Exchange Mode is enabled, it saves and regularly updates a copy of your Exchange mailbox on your computer. If you don't need this option, then turn it off and you should no longer get the error. Here are the instructions for different Outlook versions: Turn Cached Exchange Mode on and off.

Another error that may occur in the Exchange server environment is related to a missing default gateway setup. I'm not really sure what it actually means, but fortunately for us Microsoft has an explanation and automatic fix for Outlook 2007 and 2010. You can download it from this page.

One more cause of errors when starting Outlook is disabling the Encrypt data between Outlook and Microsoft Exchange setting. If it is the case, you will see the errors like these:

Unable to open your default e-mail folders. The Microsoft Exchange Server computer is not available" or "Cannot start Microsoft Office Outlook.

And again, Microsoft has provided the detailed information on how to cope with this problem, you can find it on this page.

Additionally, clearing Outlook cache may help.

A fix for Outlook Connector errors

If you cannot start Outlook because of an error message similar to this one: "Cannot start Microsoft Outlook. MAPI was unable to load the information service msncon.dll. Be sure the service is correctly installed and configured", know that it is the Microsoft Hotmail Connector add-in to blame.

In this case, uninstall the Outlook Connector manually as recommended on this forum, and then install it anew. Here are the download links:

• Outlook Hotmail Connector 32-bit
• Outlook Hotmail Connector 64-bit